import IPython.nbconvert.exporters.pdf as pdf f = open('book.tex', 'r', encoding="iso-8859-1") filedata = f.read() f.close() newdata = filedata.replace('\chapter{Preface}', '\chapter*{Preface}') f = open('book.tex', 'w', encoding="iso-8859-1") f.write(newdata) f.close() p = pdf.PDFExporter() p.run_latex('book.tex')